Anti-Cleaved IL-1b (Asp116) | Host: Rabbit | | Isotype: IgG | | Immunogen: a synthetic peptide corresponding to amino acids from the N-terminus of the mature form of IL-1b | | Form: Liquid | | Formulation: In 150 mM NaCl, 10 mM sodium HEPES, 100 µg/ml BSA, 50% glycerol, pH 7.5. | | Preservative: None | | Positive Control: Lipopolysaccharide (LPS) treated THP-1 cells | | Negative Control: Normal rabbit IgG (Cat. No. NI01) | | Comments: Recognizes the ~17 kDa IL-1b that is cleaved from the 31 kDa precursor by caspase-1 in LPS-treated THP-1 cells. Does not detect the precursor from of IL-1b. | | Ref.: Burns, K., et al. 1998. J. Biol. Chem. 273, 12203. |
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