 |
 | -20°C |  | Blue ice | | Note: Store and Ship conditions may differ. | | See Key |
|
|
|
|
| | Anti-Caspase-1 Mouse mAb (14F468) |
|  | Cat. No. AP1043 |
|
Anti-CASP1
Anti-ICE
Anti-IL-1b-converting enzyme
Anti-IL-1BC
Anti-Interleukin-1b convertase
Anti-Interleukin-1b-converting enzyme | Host: Mouse | | Isotype: IgG1 | | Immunogen: a synthetic peptide (RKVRFSFEQPDGRAQMPTTE) corresponding to amino acids 371-390 of human caspase-1 | | Form: Liquid | | Formulation: In PBS. | | Preservative: ≤ 0.1% sodium azide | | Positive Control: HeLa and NIH 3T3 cells and colon carcinoma | | Comments: Recognizes the ~45 kDa latent form of caspase-1 in HeLa and NIH3T3 cells. Also recognizes cleaved forms of caspase-1 that retain amino acids 371-390. | | Ref.: Tatsuta, T., et al. 2000. J. Biol. Chem. 275, 14248. Li, P., et al. 1995. Cell 80, 401. Yuan, J., et al. 1993. Cell 75, 641. Cerretti, D.P., et al. 1992. Science 256, 97. |
|
 | Related information for this product is available: | |
| |
EMD Chemicals Inc. EUR list price is displayed (pricing with local distributors may vary). NOTE: In Stock status is based on item availability worldwide.
Detection of human and mouse caspase-1 by immunoblotting. Samples: Whole cell lysate from HeLa (lane A) and NIH3T3 cells (lane B). Primary antibody: Anti-Caspase-1 Mouse mAb (14F468) (Cat. No. AP1043) (0.1 µg/ml, HeLa lysate and 2 µg/ml, NIH3T3 lysate). Detection: chemiluminescence.
Detection of human caspase-1 by staining paraffin sections. Sample: Colon carcinoma, formalin-fixed (panels A and B). Primary antibody: Anti-Caspase-1 Mouse mAb (14F468) (Cat. No. AP1043). Detection: DAB with hematoxylin counterstain.
|
|
|
