The lead article, Poly(ADP-ribosylation) - PARP in DNA Repair and Apoptosis, describes the structure and function of human PARP, which is a major target for drugs being designed to treat a number of diseases, such as cancer, diabetes, inflammation, and retroviral infection.
This issue contains the following groups of products: - 15 Antibodies for DNA Damage and Repair - 10 PARP Inhibitors and the PARP Cleavage Detection Kit - DNA-Dependent Protein Kinase (DNA-PK) Inhibitors - Antibodies for DNA-Dependent Protein Kinases - p21-Acitvated Kinase Inhibitor and Negative Control - 4 Apoptosis Activators - Viral Proteases - Kits for Apoptosis Research - 5 Pifithrins: Inhibitors of p53 Action - 8 Protein Kinase Inhibitors - Inhibitors of Akt/PI-3 Kinase Signaling - ERK Inhibitors - 13 Recombinant Protein Tyrosine Kinases - 6 Products in the Neurochemical Corner - Inhibitors of Angiogenesis - 4 Receptor Tyrosine Kinases and 4 PhosphoDetect Antibodies for Angiogenesis Research - 5 Proteasome/Ubiquitination Reasearch Products
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