SAP Kinase, Phospho-Specific (Thr183/Tyr185) ELISA Kit | Format: 96-well plate | | Form: 96 Tests | | Detection Method: Colorimetric | | Species Reactivity: human | | Sensitivity: ≤0.8 units/ml | | Assay Range: 1.6-100 units/ml | | Assay Time: 4 h | | Sample Type: Cell lysates | | Kit Contents: Coated 96-Well Plate, JNK1/2 Phospho-Thr183/Tyr185 Standard, Diluents, Detector Antibody, Secondary Antibody, Wash Buffer, TMB Substrate, Stop Solution, Plate Covers, and a user protocol. | | Comments: Detects the dually phosphorylated forms of JNK1 and JNK2 at Thr183 and Tyr185 in human samples. This activation occurs via a variety of signals including growth factors, inflammatory cytokines, and environmental stress. | | Ref.: Kuhl, M. 2002. Semin. Cell Dev. Biol. 13, 243. Levresse, V., et al. 2002. Mol. Pharmacol. 262, 689. Weston, C.R., et al. 2002. Science 296, 2345. Chen, N., et al. 2001. Cancer Res. 61, 3908. Dong, C., et al. 2001. J. Clin. Immunol. 21, 253. Tournier, C., et al. 2001. Genes Dev. 15, 1419. Tournier, C., et al. 2000. Science 288, 870. Leppa, S. and Bohmann, D. 1999. Oncogene 18, 6158. Davis, R.J., 1997. Cell 103, 239. Bogoyevitch, M.A., et al. 1995. J. Biol. Chem. 270, 29710. |
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