| Format: 96-well plate | | Form: 96 Tests | | Detection Method: Colorimetric | | Species Reactivity: human | | Assay Range: 62.5-2000 pg/ml | | Assay Time: 6 h | | Sample Type: Cell or tissue extracts, serum, or plasma | | Kit Contents: Coated 96-Well Plate Strips, EGF-R Standard, Standard Diluent, Detector Antibody, Streptavidin-HRP, Substrate, Plate Wash Concentrate, Stop Solution, Plate Sealers, and a user protocol. | | Comments: A sensitive assay for the detection of EGF receptor, a transmembrane glycoprotein involved in the regulation of cell proliferation, differentiation, and survival. EGF receptor is overexpressed in a variety of tumor cell lines. | | Ref.: Fuller, G.N., et al. 1992. Mut. Res. 276, 299. Klijn J.G.M., et al. 1992 Endocrine Rev. 13, 3. Wright, C., et al. 1992. Br. J. Cancer 65, 118. Carpenter, G. 1987. Annual Rev. Biochem. 56, 881. Yarden, Y., and Ullrich, A. 1988. Annual Rev Biochem. 57, 443. Cadena, D.L., and Gill, G.N. 1992. FASEB J. 6, 2332. Koenders, P.G., et al. 1991. Cancer Res. 51, 4544. McKenzie S.J. 1991. Biochim. Biophys Acta 1072, 193. Nicholson, S., et al. 1991. Diag. Oncol. 1, 43. Nicholson, S.,et al. 1991. Br. J. Cancer 63, 146. Wright, C., et al. 1991. Br. J. Cancer 63, 967. Ullrich, A., and Schlessinger, J. 1990. Cell 61, 203. Rios, M.A., et al. 1988. Anticancer Res. 8, 173. Kraus, M.H., et al. 1987. EMBO J. 6, 605. Sainsbury, J.R.C., et al. 1987. Lancet 1, 1398. Carlin, C.R.,et al. 1986. Mol. Cell. Biol. 6, 257. Gullick, W.J., et al. 1986. Cancer Res. 46, 285. Ozanne, B., et al. 1986. J. Pathol 149, 9. Downward, J., et al. 1984. Nature 307, 521. Ullrich, A.L., et al. 1984. Nature 309, 418. Mayes, F.L.V., and Waterfield, M.D. 1984. EMBO J. 3, 531. Schreiber, A.B., et al. 1983. J. Biol Chem. 258, 846. Waterfield, M.D., et al. 1982. J. Cell. Biochem. 20, 149 Cohen, S., et al. 1980. J. Biol. Chem. 258, 4834. Carpenter, G., and Cohen, S., 1979. Ann Rev. Biochem. 48, 193. Wrann, M.M., et al. 1979. J. Biol. Chem. 254, 8083. Fabricant, R.N., et al. 1977. Proc. Natl. Acad. Sci. USA 74, 565. | | Sold under license of U.S. Patent 4,943,533 and 5,674,753. | |