| Format: 96-well plate | | Form: 96 Tests | | Detection Method: Colorimetric | | Species Reactivity: human, mouse, rat | | Sensitivity: < 1.6 ng/ml | | Assay Range: 1.6-100 ng/ml | | Assay Time: 4 h | | Kit Contents: FAK Standard, Standard Diluent Buffer, FAK Antibody-Coated 96-Well Plate, Rabbit Anti-FAK Detector Antibody, Goat Anti-Rabbit IgG-HRP Concentrate, HRP Diluent, Wash Buffer Concentrate, TMB, Stop Solution, Plate Covers and a user protocol. | | Comments: Detects and quantifies the level of FAK (Focal Adhesion Kinase) protein independent of its phosphorylation state in human, mouse and rat cells. FAK is a non-receptor tyrosine kinase that has been implicated in several cell processes including the regulation of cell motility, cell morphology and cell adhesion. | | Ref.: Crowe, D.L., et al. 2004. BMC Cancer 4, 18. Xu, L.H., et al. 2004. J. Biol. Chem. 275, 30597. Yu, H.G., et al. 2004. Biochem. Pharmacol. 67, 135. Lee, J.W., et al. 2003. J. Orthop. Res. 21, 1071. Streblow, D.N., et al. 2003. J. Biol. Chem. 278, 50456. Jones, G., et al. 2001. Cancer Res. 61, 4978. Ruest, P.J., et al. 2000. Cell Growth Differ. 11, 41. Igishi, T., et al. 1999. J. Biol. Chem. 274, 30738. Owen, J.D., et al. 1999. Mol. Cell. Biol. 19, 4806. Sieg, D.J., et al. 1999. J. Cell Sci. 112, 2677. Cary, L.A., et al. 1996. J. Cell Sci. 109, 1787. | |