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| | Anti-Cyclin D1 (Ab-3) Mouse mAb (DCS-6) |
|  | Cat. No. CC12 |
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Anti-Bcl-1
Anti-PRAD-1 | Host: Mouse | | Isotype: IgG2a | | Immunogen: recombinant human cyclin D1 | | Form: Liquid | | Formulation: In 50 mM sodium phosphate buffer, 0.2% gelatin. | | Preservative: ≤0.1% sodium azide | | Positive Control: MCF7, or A431 cells or breast carcinoma tissue | | Negative Control: trp E (Ab-1) | | Comments: Recognizes cyclin D1 in MCF-7 and A431 cells. Does not react with cyclins D2 and D3. | | Ref.: Inaba, T., et al. 1992. Genomics 13, 565. Jiang, W., et al. 1992. Cancer Res. 2, 2980. Pines, J. 1992. Cell Growth Differ. 2, 305. Xiong, Y., et al. 1992. Genomics 13, 575. Xiong, Y., et al. 1992. Cell 71, 504. Motokura, T., et al. 1991. Nature 350, 512. Solomon, M.J., et al. 1990. Cell 63, 1013. Draetta, G., and Beach, D. 1988. Cell 54, 17. |
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| DCS-6 | human, mouse, rat | FC, FS, IB, IF, IP, NT, PS
See Key |
Detection of cyclin D1 from MCF7 cell lysates using Cat. No. CC12 with chemiluminescent detection. Courtesy of J. Bartek, Danish Cancer Society.
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| - Takeshi Shimamura, et al. (2005) Epidermal growth factor receptors harboring kinase domain mutations associate with the heat shock protein 90 chaperone and are destabilized following exposure to geldanamycins. Cancer Research 65, 6401-6408.
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