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| | PhosphoDetect™ Anti-Chk2 (pThr68) Rabbit pAb |
|  | Cat. No. DR1026 |
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| Host: Rabbit | | Isotype: IgG | | Immunogen: a synthetic phosphopeptide corresponding to amino acids surrounding the Thr68 phosphorylation site of human Chk2 | | Form: Liquid | | Formulation: In 150 mM NaCl, 10 mM HEPES, 100 µg/ml BSA, 50% glycerol, pH 7.5. | | Preservative: None | | Positive Control: HEK 293 cells treated with UV or doxorubicin | | Comments: Recognizes the ~62-66 kDa Chk2 protein phosphorylated at Thr68 in UV- or doxorubicin-treated HEK293 cells. | | Ref.: Eastman, A., et al. 2002. Mol. Cancer Ther. 1, 1067. Kohn, E.A., et al. 2002. J. Biol. Chem. 277, 26564. Ahn, J.Y., et al. 2000. Cancer Res. 60, 5934. Matsuoka, S., et al. 2000. Proc. Natl. Acad. Sci. USA 97, 10389. |
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EMD Chemicals Inc. list price is displayed (pricing with local distributors may vary). NOTE: In Stock status is based on item availability worldwide.
| | human, monkey | FC, IB, IC, IH, IP
See Key |
Detection of human Chk2, phosphorylated at Thr68, by immunoblotting. Samples: Whole cell lysate from HEK293 cells, left untreated (lane 1), treated with UV (lane 2), or treated with 0.5 µM doxorubicin (Cat. No. 324380) (lane 3). Primary antibody: PhosphoDetect™ Anti-Chk2 (pThr68) Rabbit pAb (Cat. No. DR1026). Detection: chemiluminescence.
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