Anti-Insulin Receptor Substrate-1, Phospho-Specific (Ser307) | Host: Rabbit | | Isotype: IgG | | Immunogen: a synthetic phosphopeptide (SITATpSPASMVGGK) corresponding to amino acids 301-315 surrounding the Ser307 phosphorylation site of mouse IRS-1 | | Form: Liquid | | Formulation: In PBS, 1 mg/ml BSA. | | Preservative: ≤0.1% sodium azide | | Positive Control: 3T3-L1 cells treated with insulin | | Comments: Recognizes the ~165-180 kDa IRS-1 protein phosphorylated at Ser307 in insulin-treated 3T3-L1 cells. | | Ref.: Gaul, P., et al. 2003. J. Biol. Chem. 278, 26550. Aguirre, V., et al. 2002. J. Biol. Chem. 277, 1531. Rui, L., et al. 2001. J. Clin. Invest. 107, 181. | |