| | Anti-IGF-IR (Ab-1) Mouse mAb (aIR3) |
|  | Cat. No. GR11T |
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Anti-IGF-R
Anti-Insulin-Like Growth Factor Receptor | Host: Mouse | | Isotype: IgG1 | | Immunogen: partially purified, human placenta IGF-IR receptor | | Form: Liquid | | Formulation: In 0.05 M sodium phosphate buffer, 50% glycerol. | | Preservative: None | | Positive Control: HepG2 cells | | Negative Control: HS27 cells | | Comments: Recognizes the ~130 kDa a- and ~90 kDa b-subunits of the IGF-I receptor. For neutralization studies Cat. No. GR11L is recommended. | | Ref.: Roth, R. 1988. Science 239, 1269. Rohlik, Q.T., et al. 1987. Biochem. Biophys. Res. Comm. 149, 276. Rosen, O.M., 1987. Science 257, 1452. Rechler, M.M. and Nissley, S.P., 1986. Hormone Res. 24, 152. Ullrich, A., et al. 1986. EMBO J. 5, 2503. Zapf, S. and Froesch, E.R., 1986. Hormone Res. 24, 121. Humbel, R.E., 1984. I. Chemistry; in Li Hormonal proteins and peptides. Vol 12, Chap. 4 (Academic Press, New York). |
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EMD Chemicals Inc. list price is displayed (pricing with local distributors may vary). NOTE: In Stock status is based on item availability worldwide.
| αIR3 | human | IF, IP, NOT IB, NOT PS
See Key |
EMD Chemicals Inc. list price is displayed (pricing with local distributors may vary). NOTE: In Stock status is based on item availability worldwide.
| Anti-IGF-IR (Ab-1) Mouse mAb (aIR3) | GR11 | 100 µg | Y | N/A |
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| - Rita Nahta, et al. (2005) Insulin-like growth factor-I receptor/human epidermal growth factor receptor 2 heterodimerization contributes to trastuzumab resistance of breast cancer cells. Cancer Research 65, 11118-11128.
- Daniel E. Syroid, et al. (1999) A role for insulin-like growth factor-I in the regulation of Schwann cell survival. Journal of Neuroscience 19, 2059-2068.
- Donald M. Henricks, et al. (1998) Identification of insulin-like growth factor I in bovine seminal plasma and its receptor on spermatozoa: influence on sperm motility. Biology of Reproduction 59, 330-337.
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