Anti-IGF-R Anti-Insulin-Like Growth Factor Receptor | Host: Mouse | | Isotype: IgG1 | | Immunogen: recombinant, human, soluble IGF-I receptor | | Epitope: Extracellular domain of IGF-I Receptor | | Form: Lyophilized | | Formulation: Lyophilized from PBS, 20 mM ammonium bicarbonate, ≤5% trehalose, 100 µg BSA. | | Preservative: None | | Positive Control: Recombinant IGF-I receptor protein or MCF7 cells | | Comments: Recognizes the ~250-260 kDa IGF-1 receptor protein in MCF-7 cells. Does not cross-react with recombinant human IGF-I binding protein 1, IGF-I, or IGF-II. | | Ref.: Leroith, D., and Roberts, C. T., 2003. Cancer Letter 195, 127. Dore, S., et al. 1997. Trends Neurosci. 20, 326. Dore, S., et al. 1997. Proc. Natl. Acad. Sci. USA 94, 4772. Walter, H.J., et al. 1997. Endocrinology 138, 3024. Beilharz, E.J., et al. 1995. Mol. Brain Res. 29, 81. Jones, J.I. and Clemmons, D.R. 1995. Endocr. Rev. 16, 3. | |