| Host: Mouse | | Isotype: IgG2a | | Immunogen: mature, human cathepsin D | | Form: Liquid | | Formulation: In 50 mM sodium phosphate buffer, 0.2% gelatin, pH 7.5. | | Preservative: ≤0.1% sodium azide | | Positive Control: SK-HEP-1 concentrated conditioned medium or breast carcinoma tissue | | Comments: Recognizes the ~52 kDa latent form, the ~48 kDa mature form, and the ~34 kDa subunit of cathepsin D in breast carcinoma tissue extracts. | | Ref.: Rochefort, H. 1992. Eur. J. Cancer. 28A, 1780. Rochefort, H. 1990. in Seminars in Cancer Biology, ed. M.M. Gottesman. Vol. 1(2), 153. Westly, B. and Rochefort, H. 1980. Cell 20, 352. Barrett, A.J. 1977. in Proteinases in Mammalian Cells and Tissues, ed. Barret, A.J. (North Holland, New York), pp. 209. | |