| Host: Rabbit | | Isotype: IgG | | Immunogen: purified human liver cathepsin D | | Form: Liquid | | Formulation: In 50 mM sodium phosphate buffer, 0.2% gelatin, pH 7.5. | | Preservative: ≤0.1% sodium azide | | Positive Control: HT1080 concentrated conditioned medium or breast carcinoma tissue | | Comments: Recognizes the ~52 kDa latent form D and the ~34 kDa subunit, but not the ~14 kDa subunit of cathepsin D in breast carcinoma tissue extracts. | | Ref.: Rochefort, H. 1992. Eur. J. Cancer 28A, 1780. Rochefort, H. 1990. In Seminars in Cancer Biology, ed. M. M. Gottesman. Vol. 1(2), 153. Westly, B. and Rochefort, H. 1980. Cell 20, 352. Barret, A. J. 1977. In Proteinases in Mammalian Cells and Tissues, ed. Barret, A. J., North Holland, New York, p 209. | |