Anti-Plasminogen Activator Inhibitor-1

Host: Mouse

Isotype: IgG1

Immunogen: partially purified PAI-1 from conditioned medium of dexamethasone-treated HT1080 human cells

Form: Lyophilized

Formulation: Lyophilized from a volatile buffer, 100 µg BSA.

Preservative: None

Positive Control: Conditioned media from dexamethasone-treated (1 µM) HT-1080 cells

Comments: Recognizes both active and latent forms of the ~50 kDa PAI-1 protein in conditioned media from dexamethasone-treated HT-1080 cells. Sold under license of U.S. Patent 5,422,245.

Ref.: Janicke, F., et al. 1994. Cancer Research. 54, 2527. Lawrence, D. A., et al. 1994. J. Biol. Chem. 269, 15223. Nagayama, M., et al. 1994. Cancer 73, 1398. Petersen, H., et al. 1994. Cancer Res. 54, 120. Keijer, J., et al. 1991. Blood 78, 401. Blasi, F. and Verde, P., 1990. in Seminars in Cancer Biol. Vol. 1, 153. Declerck, P. J. and Collen, D., 1990. Thrombosis Res. Supplement X 3. Nielsen, L. S., et al. 1986. Thrombosis and Haemostasis. 55, 206.

Sold under license of U.S. Patent 5,422,245.