Anti-Tissue Inhibitor of Metalloproteinase-1

Host: Mouse

Isotype: IgG1

Immunogen: recombinant, human TIMP-1

Form: Liquid

Formulation: In 10 mM PBS, 0.2% BSA, pH 7.4.

Preservative: ≤0.1% sodium azide

Positive Control: Cytotrophoblastic columns, endothelial or fibroblastic stromal cells of villi, large decidualized cells of decidual membrane in placenta, or breast carcinoma

Comments: Recognizes the ~28.5 kDa TIMP-1 protein in endothelial cells, fibroblasts, and breast carcinoma tissue.

Ref.: Herbst, H., et al. 1997. Am. J. Pathol. 150, 1647. Jung, K., et al. 1997. Int. J. Cancer 74, 220. Rivera, S., et al. 1997. J. Neurosci. 17, 4223. Vallon, R., et al. 1997. Eur. J. Biochem. 244, 81. Hurskainen, T., et al. 1996. J. Histochem. Cytochem. 44, 1379. Cottam, D.W. and Rees, R.C. 1993. Intl J. Oncol. 2, 861. Stetler-Stevenson, W.G., et al. 1993. FASEB J. 7, 1434. Woessner, J.F. 1991. FASEB J. 5, 2145. Liotta, L.A. and Stetler-Stevenson, W.G. 1990. in Seminars in Cancer Biology, ed. M.M. Gottesman. Vol. 1(2), 99.

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