| Host: Mouse | | Isotype: IgG2a | | Immunogen: partially purified mouse p53 | | Epitope: within amino acids 376-378 of human p53 | | Form: Liquid | | Formulation: In 50 mM sodium phosphate buffer, 0.2% gelatin, pH 7.5. | | Preservative: ≤0.1% sodium azide | | Positive Control: Breast carcinoma, A431 cells, or p53 standard (Cat. No. 506147) | | Negative Control: SK-OV-3 cells or normal skin | | Comments: Recognizes the ~53 kDa mammalian wild-type and mutant p53 protein. Does not recognize phosphorylated or acetylated p53. | | Ref.: El-Deiry, W.S., et al. 1994. Cancer Res. 54, 1169. Greenblatt, M.S., et al. 1994. Cancer Res. 54, 4855. Legros, Y., et al. 1994. Oncogene 9, 2071. Barak, Y., et al. 1993. EMBO J. 12, 461. Kuerbitz, S.J. 1992. Proc. Natl. Acad. Sci. USA 89, 7491. Kastan, M.B., et al. 1992. Cell 71, 587. Lane, D.P. 1992. Nature 358, 15. Kastan, M.B., et al. 1991. Cancer Res. 51 6304. Crawford, L. and Harlow, E. 1982. J. Virol. 41, 709. Harlow, E., et al. 1981. J. Virol. 39 861. |
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