| Host: Mouse | | Isotype: IgG2a | | Immunogen: partially purified mouse p53 | | Epitope: within amino acids 376-378 of human p53 | | Form: Lyophilized | | Formulation: Lyophilized from a volatile buffer, 100 µg BSA. | | Preservative: None | | Positive Control: Breast carcinoma, A431 cells, or p53 standard (Cat. No. 506147) | | Negative Control: Normal skin tissue or SK-OV-3 cells | | Comments: Recognizes the ~53 kDa mammalian wild-type and mutant p53 protein. Does not recognize phosphorylated p53. | | Ref.: El-Deiry, W.S., et al. 1994. Cancer Res. 54, 1169. Greenblatt, M.S., et al. 1994. Cancer Res. 54, 4855. Legros, Y., et al. 1994. Oncogene 9, 2071. Barak, Y., et al. 1993. EMBO J. 12, 461. Kuerbitz, S.J. 1992. Proc. Natl. Acad. Sci. USA 89, 7491. Kastan, M.B., et al. 1992. Cell 71, 587. Lane, D.P. 1992. Nature 358, 15. Kastan, M.B., et al. 1991. Cancer Res. 51 6304. Crawford, L. and Harlow, E. 1982. J. Virol. 41, 709. Harlow, E., et al. 1981. J. Virol. 39 861. | |