Anti-ErbB2
Anti-Erythroblastosis Virus
Anti-HER2
Anti-c-Neu

Host: Mouse

Isotype: IgG1

Immunogen: cells overexpressing human c-ErbB2/c-Neu

Form: Liquid

Formulation: In 50 mM sodium phosphate buffer, 0.2% gelatin.

Preservative: ≤0.1% sodium azide

Positive Control: SK-BR-3 cells or breast carcinoma tissue

Negative Control: Normal skin tissue or HepG2 cells

Comments: Recognizes the ~185 kDa c-ErbB2/c-Neu protein in SK-BR-3 cells and breast carcinoma tissue. Does not cross-react with v-ErbB2 or the EGF receptor.

Ref.: Van De Vijver, M.J., et al.1988 New Engl. J. Med. 319, 1239. DiFiore, P.P., et al.1987 Science 237, 178. Slamon, D.J., et al. 1987 Science 235, 177. Varley, J.M., et al.1987 Oncogene 1, 423. Bargmann, C.I., et al. 1986 Nature 319, 226. Yamamoto, T., et al.1986 Nature 319, 230. Blick, M., et al. 1984 Blood 64, 1234.