Calbiochem: OP15L: Anti-c-ErbB2/c-Neu (Ab-3) Mouse mAb (3B5)

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��	Anti-c-ErbB2/c-Neu (Ab-3) Mouse mAb (3B5)

Cat. No. OP15L��

All Categories � Calbiochem � Antibodies � Primary Antibodies � Kinases � Tyrosine

Anti-ErbB2
Anti-Erythroblastosis Virus
Anti-HER2
Anti-Human Epidermal Growth Factor
Anti-Neu

Host: Mouse
Isotype: IgG₁
Immunogen: a synthetic peptide (TAENPEYLGLDVPV) corresponding to amino acids 1242-1255 from the C-terminal domain of human c-ErbB2/c-Neu
Form: Lyophilized
Formulation: Lyophilized from 20 mM ammonium bicarbonate Buffer, 100 �g FAF-BSA.
Preservative: None
Positive Control: SK-BR-3 cells or breast carcinoma tissue
Negative Control: HepG2 cells or normal skin
Comments: Recognizes the ~185 kDa c-ErbB2/c-Neu protein in HEK293 cells.
Ref.: Mamcs, J.R., et al. 1994. Ann. Surg. 219, 332. Tetu, B., et al. 1994. Cancer 73, 2359. DiFiore, P.P., et al. 1987. Science 237, 178. Slamon, D.J., et al. 1987. Science 235, 177. Varley, J.M., et al. 1987. Oncogene 1, 423. Bargmann, C.I., et al. 1986. Nature 319, 226. Yamamoto, T., et al. 1986. Nature 319, 230. Blick, M., et al. 1984. Blood 64, 1234. Schwab, M., et al. 1984. Cold Spring Harbor Laboratory 2, 215.

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100 �g Y N/A

Clone Species Reactivity Application
3B5� human, mouse FS, IB, IF, IP, PS�
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Detection of human c-ErbB2/c-Neu by immunoblotting. Sample: Whole cell lysate from HEK293 cells. Primary antibody: Anti-c-ErbB2/c-Neu (Ab-3) Mouse mAb (3B5) (Cat. No. OP15L) (1 �g/ml). Detection: chemiluminescence.

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OP15L: Anti-c-ErbB2/c-Neu (Ab-3) Mouse mAb (3B5) - English
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Related Categories:
All Categories � Calbiochem � Antibodies � Primary Antibodies � Kinases � Tyrosine

Selected Citations:
Rita Nahta, et al. (2005) Insulin-like growth factor-I receptor/human epidermal growth factor receptor 2 heterodimerization contributes to trastuzumab resistance of breast cancer cells. Cancer Research 65, 11118-11128.

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