Calbiochem: OP15T: Anti-c-ErbB2/c-Neu (Ab-3) Mouse mAb (3B5)

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��	Anti-c-ErbB2/c-Neu (Ab-3) Mouse mAb (3B5)

Cat. No. OP15T��

All Categories � Calbiochem � Antibodies � Primary Antibodies � Kinases � Tyrosine

Anti-ErbB2
Anti-Erythroblastosis Virus
Anti-HER2
Anti-c-Neu

Host: Mouse
Isotype: IgG₁
Immunogen: a synthetic peptide (TAENPEYLGLDVPV) corresponding to amino acids 1242-1255 from the C-terminal domain of human c-neu
Form: Liquid
Formulation: In 50 mM sodium phosphate buffer, 50% glycerol, pH 7.5.
Preservative: None
Positive Control: SK-BR-3 cells or breast carcinoma tissue
Negative Control: HepG2 cells or normal skin
Comments: Recognizes the ~185 kDa c-ErbB2/c-Neu protein in HEK293 cells.
Ref.: Mamcs, J.R., et al. 1994. Ann. Surg. 219, 332. Tetu, B., et al. 1994. Cancer 73, 2359. DiFiore, P.P., et al. 1987. Science 237, 178. Slamon, D.J., et al. 1987. Science 235, 177. Varley, J.M., et al. 1987. Oncogene 1, 423. Bargmann, C.I., et al. 1986. Nature 319, 226. Yamamoto, T., et al. 1986. Nature 319, 230. Blick, M., et al. 1984. Blood 64, 1234. Schwab, M., et al. 1984. Cold Spring Harbor Laboratory 2, 215.

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10 �g Y N/A

Clone Species Reactivity Application
3B5� human, mouse FS, IB, IF, IP, PS�
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Anti-c-ErbB2/c-Neu (Ab-3) Mouse mAb (3B5) OP15 100 �g Y N/A*

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Cat. No.	Disclaimers


OP15	Canadian Export Regulations	Due to the country and/or U.S. state of origin of the animal material used in this product, this product may not be exported to Canada.

Detection of human c-ErbB2/c-neu by immunoblotting. Sample: Whole cell lysate (56 mg) from MCF-7 cells. Primary antibody: Anti-c-ErbB2/c-Neu (Ab-3) Mouse Mab (3B5) (Cat. No. OP15) (1 mg/ml). Detection: chemiluminescence.

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OP15T: Anti-c-ErbB2/c-Neu (Ab-3) Mouse mAb (3B5) - English
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Related Categories:
All Categories � Calbiochem � Antibodies � Primary Antibodies � Kinases � Tyrosine

Selected Citations:
Rita Nahta, et al. (2005) Insulin-like growth factor-I receptor/human epidermal growth factor receptor 2 heterodimerization contributes to trastuzumab resistance of breast cancer cells. Cancer Research 65, 11118-11128.

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