Anti-Abl Anti-p150 | Host: Mouse | | Isotype: IgG1 | | Immunogen: a TrpE-v-Abl fusion protein | | Form: Liquid | | Formulation: In 50 mM sodium phosphate buffer, 0.2% gelatin. | | Preservative: ≤0.1% sodium azide | | Positive Control: K562 (human bcr/abl protein), ANN-1 (mouse abl protein), HL-60 (human normal abl protein), or NIH 3T3 (mouse normal abl protein) cells | | Comments: Recognizes the ~145 kDa human c-Abl, the ~150 kDa mouse c-Abl, v-Abl proteins, and the Bcr/Abl translocation products in ALL (~190 kDa) and CML (~210 kDa). | | Ref.: Wiedemann, L.M., et al. 1988. Blood 71, 349. Schiff-Maker, L., Buet al. 1986. J. Virol. 57, 1182. Stam, K., et al. 1985. N. Engl. J. Med. 313, 1429. Konopka, J.B., et al. 1984. Cell 37, 1035. Prywes, R., et al. 1983. Cell 34, 569. de Klein, et al. 1982. Nature 300, 765. 1982. Reynolds, F.H., et al. 1980. J. Virol. 36, 374. Reynolds, F.H., et al. 1978. Proc. Natl. Acad. Sci. USA 75, 3974. Witte, O.N., et al. 1978. Proc. Natl. Acad. Sci. USA 75, 2488. 1978. Abelson, H.T. and Rabstein, L.S. 1970. Cancer Res. 30, 2213. | |