Host: Mouse

Isotype: IgG2b

Immunogen: recombinant p21 Ras

Epitope: within the N-terminus

Form: Liquid

Formulation: In 0.05 M sodium phosphate buffer, 0.2% gelatin.

Preservative: ≤0.1% sodium azide

Positive Control: Sw480 or Y1 cells or normal skin tissue

Comments: Recognizes the ~21 kDa H-, K-, and N-Ras proteins including both c- and v- Ras in SW480 and Y1 cells and normal skin tissue.

Ref.: Rodenhuis, S. et al., 1992 Cancer Res. (Suppl) 52, 2665s. Sidransky, D., et al., 1992 Science 256, 102. Bos, J.L., 1988 Mutation Res. 195, 255. Furth, M. E., et al., 1987. Oncogene 1, 47. Kraus, M.H., et al., 1984 Proc. Natl. Acad. Sci. USA 81, 5384. Shimizu, K., et al., 1983 Proc. Natl. Acad. Sci. USA 80, 2112. Taparowsky, E., et al.,1983 Cell 34, 581. Ellis, R.W., et al., 1981 Nature 292, 506. Shih, T.Y., et al., 1980 Nature 287, 686.