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| | Anti-c-H-Ras (Ab-1) Mouse mAb (F235-1.7.1) | |  | Cat. No. OP23 | |
| Host: Mouse | | Isotype: IgG1 | | Immunogen: recombinant p21 Ras | | Epitope: within amino acids 54-188 | | Form: Liquid | | Formulation: In 50 mM sodium phosphate buffer, 0.2% gelatin, pH 7.4. | | Preservative: ≤0.1% sodium azide | | Positive Control: Normal skin tissue or ras 1 cells | | Comments: Recognizes the ~21 kDa c-H-Ras protein in normal skin tissue and Rat1 cells. Does not react with c-K-Ras or c-N-Ras p21. A doublet may be seen due to farnesylation. | | Ref.: Rodenhuis, S. et al. 1992. Cancer Res. (Suppl) 52, 2665s. Sidransky, D., et al. 1992. Science 256, 102. Bos, J.L. 1989. Cancer Res. 49, 4682. Furth, M. E., et al. 1987. Oncogene 1, 47. Kraus, M.H., et al. 1984. Proc. Natl. Acad. Sci. USA 81, 5384. Shimizu, K., et al. 1983. Proc. Natl. Acad. Sci. USA 80, 2112. Taparowsky, E., et al. 1983. Cell 34, 581. Ellis, R.W., et al. 1981. Nature 292, 506. Shih, T.Y., et al. 1980. Nature 287, 686. | |
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| F235-1.7.1 | human, mouse, rat | FS, IB, IF, IP, PS See Key |
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