| Host: Mouse | | Isotype: IgG2a | | Immunogen: recombinant, rat K-Ras | | Epitope: within amino acids 54-189 | | Form: Liquid | | Formulation: In 50 mM sodium phosphate buffer, 0.2% gelatin, pH 7.5. | | Preservative: ≤0.1% sodium azide | | Positive Control: SW480 or Y1 cells or normal skin tissue | | Comments: Recognizes c-K-Ras and v-K-Ras in SW480 and Y1 cells and normal skin tissue. Cross-reacts with c-H-Ras and c-N-Ras. | | Ref.: Mizuuchi, H. et al. 1992. Cancer Res. 2, 2777. Rodenhuis, S. et al. 1992. Cancer Res. (Suppl) 52, 2665s. Sirdransky, D., et al. 1992. Science 256, 102. Shaw, P., et al. 1991. Oncogene 6, 2121. Bos, J.L. 1989. Cancer Res. 49, 4682. Furth, M.E., et al. 1987. Oncogene 1, 47. Kraus, M.H., et al. 1984. Proc. Natl. Acad. Sci. USA 81, 5384. Shimizu, K., et al. 1983. Proc. Natl. Acad. Sci. USA 80, 2112. Taparowsky, E., et al. 1983. Cell 34, 581. Ellis, R.W., et al. 1981. Nature 292, 506. Shih, T.Y., et al. 1980. Nature 287, 686. | |