| Host: Mouse | | Isotype: IgG1 | | Immunogen: Balb/c SVA31 E7 cells | | Epitope: a conformational epitope within amino acids 85-109 | | Form: Lyophilized | | Formulation: Lyophilized from a volatile buffer, 100 µg BSA. | | Preservative: None | | Positive Control: SV-T2 cells | | Negative Control: SK-OV-3 cells | | Comments: Recognizes the ~53 kDa wild-type p53 protein in its native conformation in SV-T2 cells. Does not recognize mutant or denatured p53 protein. | | Ref.: El-Deiry, W.S., et al. 1994. Cancer Res. 54, 1169. Greenblatt, M.S., et al. 1994.Cancer Res. 54, 4855. Barak, Y., et al. 1993. EMBO J. 12, 461. Lane, D.P. 1992. Nature 358, 15. Kastan, M.B., et al. 1991. Cancer Res. 51, 6304. Kastan, M.B., et al. 1992. Cell 71, 587. Kuerbitz, S.J. 1992. Proc. Natl. Acad. Sci. USA 89, 7491. |
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