| Host: Mouse | | Isotype: IgG2a | | Immunogen: vLM mouse tumor cells | | Form: Liquid | | Formulation: In 0.05 M sodium phosphate buffer, 0.2% gelatin. | | Preservative: ≤0.1% sodium azide | | Positive Control: Hs27 cells or breast carcinoma tissue | | Comments: Recognizes the ~53 kDa wild-type p53 protein in its native conformation in Hs27 cells and breast carcinoma tissue. Does not recognize mutant or denatured p53 protein. | | Ref.: El-Deiry, W.S., et al. 1994. Cancer Res. 54, 1169. Greenblatt, M.S., et al. 1994. Cancer Res. 54, 4855. Barak, Y., et al. 1993. EMBO J. 12, 461. Kastan, M.B., et al. 1992. Cell 71, 587. Kuerbitz, S.J. 1992. Proc. Natl. Acad. Sci. USA 89, 7491. Lane, D.P. 1992. Nature 358, 15. Kastan, M.B., et al. 1991. Cancer Res. 51, 6304. Ball, R.K., et al. 1984. EMBO J. 3, 1485. | |