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  Anti-p53 (Ab-6) (Pantropic) Mouse mAb (DO-1)
Cat. No. OP43  
All Categories » Calbiochem » Antibodies » Primary Antibodies » Transcription Factors » p53

Host: Mouse
Isotype: IgG2a
Immunogen: wild type, recombinant, human p53
Epitope: Within amino acids 21-25 of human p53
Form: Liquid
Formulation: In 0.05 M sodium phosphate buffer, 0.2% gelatin.
Preservative: ≤0.1% sodium azide
Positive Control: A431 cells or breast carcinoma tissue
Negative Control: SK-OV-3 cells or normal skin tissue
Comments: Recognizes the ~53 kDa wild-type and mutant p53 protein in A431 cells and breast carcinoma tissue.
Ref.: El-Deiry, W.S., et al. 1994. Cancer Res. 54, 1169. Greenblatt, M.S., et al. 1994. Cancer Res. 54, 4855. Legros, Y., et al. 1994. Oncogene 9, 2071. Barak, Y., et al. 1993. EMBO J. 12, 461. Kastan, M.B., et al. 1992. Cell 71, 587. Kuerbitz, S.J. 1992. Proc. Natl. Acad. Sci. USA 89, 7491. Lane, D.P. 1992. Nature 358, 15. Vojtesek, B., et al. 1992. J. Immunol. Meth. 151, 237. Kastan, M.B., et al. 1991 Cancer Res. 51, 6304.

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20 µgYN/A
100 µgYN/A

CloneSpecies ReactivityApplication
DO-1 feline, human 
not mouse, not rat 
FS, IB, IC, IP, PS 
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EMD Chemicals Inc. list price is displayed (pricing with local distributors may vary). NOTE: In Stock status is based on item availability worldwide.

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Anti-p53 (Ab-6) (Pantropic) Mouse mAb (DO-1)OP43T10 µgYN/A


Detection of human p53 by immunoblotting. Sample: Whole cell lysates from A431 cells. Primary antibody: Anti-p53 (Ab-6) (Pantropic) Mouse mAb (DO-1) (Cat. No. OP43) (1 mg/ml). Detection: chemiluminescence.

Related Products:
OP43: Anti-p53 (Ab-6) (Pantropic) Mouse mAb (DO-1)
OP43A: Anti-p53 (Ab-6) (Pantropic) Mouse mAb (DO-1) Agarose Conjugate
OP43F: Anti-p53 (Ab-6) (Pantropic) Mouse mAb (DO-1) Fluorescein Conjugate
OP43L: Anti-p53 (Ab-6) (Pantropic) Mouse mAb (DO-1)
OP43T: Anti-p53 (Ab-6) (Pantropic) Mouse mAb (DO-1)

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Material Safety Data Sheets:
OP43: Anti-p53 (Ab-6) (Pantropic) Mouse mAb (DO-1) - English
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Related Categories:
All Categories » Calbiochem » Antibodies » Primary Antibodies » Transcription Factors » p53

Selected Citations:
  1. Fang Zhang, et al. (2006) Ribosomal stress couples the unfolded protein response to p53-dependent cell cycle arrest. Journal of Biological Chemistry 281, 30036-30045.
  2. Frank Staib, et al. (2005) The p53 Tumor Suppressor Network is a Key Responder to Microenvironmental Components of Chronic Inflammatory Stress. Cancer Research 65, 10255-10264.
  3. Hazel E. Warburton, et al. (2005) p53 regulation and function in renal cell carcinoma. Cancer Research 65, 6498-6503.
  4. Urs Hobom and Matthias Dobbelstein. (2004) E1B-55-kilodalton protein is not required to block p53-induced transcription during adenovirus infection. Journal of Virology 78, 7685-7697.