| Host: Mouse | | Isotype: IgG2a | | Immunogen: wild type, recombinant, human p53 | | Epitope: within amino acids 21-25 | | Form: Liquid | | Formulation: In 50 mM sodium phosphate buffer, 50% glycerol, pH 7.5. | | Preservative: None | | Positive Control: A431, HeLa, or SK-BR-3 cells or breast carcinoma tissue | | Negative Control: SK-OV-3 cells or normal skin tissue | | Comments: Recognizes the ~53 kDa wild-type and mutant p53 protein in A431 cells. | | Ref.: El-Deiry, W.S., et al. 1994. Cancer Res. 54, 1169. Greenblatt, M.S., et al. 1994. Cancer Res. 54 4855. Barak, Y., et al. 1993. EMBO J. 12, 461. Kastan, M.B., et al. 1992. Cell 71, 587. Kuerbitz, S.J. 1992. Proc. Natl. Acad. Sci USA 89, 7491. Lane, D.P. 1992. Nature 358, 15. Kastan, M.B., et al. 1991. Cancer Res. 51, 6304. |
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