| Host: Mouse | | Isotype: IgG2a | | Immunogen: wild type, recombinant, human p53 | | Epitope: Within amino acids 21-25 of p53 | | Form: Liquid | | Formulation: In 0.05 M sodium phosphate buffer, 50% glycerol. | | Preservative: None | | Positive Control: A431 cells or breast carcinoma tissue | | Negative Control: SK-OV-3 cells or normal skin tissue | | Comments: Recognizes the ~53 kDa wild-type and mutant p53 protein in A431 cells and breast carcinoma tissue. | | Ref.: El-Deiry, W.S., et al. 1994. Cancer Res. 54, 1169. Greenblatt, M.S., et al. 1994. Cancer Res. 54, 4855. Legros, Y., et al. 1994. Oncogene 9, 2071. Barak, Y., et al. 1993. EMBO J. 12, 461. Kastan, M.B., et al. 1992. Cell 71, 587. Kuerbitz, S.J. 1992. Proc. Natl. Acad. Sci. USA 89, 7491. Lane, D.P. 1992. Nature 358, 15. Vojtesek, B., et al. 1992. J. Immunol. Meth. 151, 237. Kastan, M.B., et al. 1991 Cancer Res. 51, 6304. | |