Anti-Adenomatous Polyposis Coli

Host: Mouse

Isotype: IgG2b

Immunogen: a recombinant protein consisting of the N-terminal 226 amino acids of APC

Form: Liquid

Formulation: In 50 mM sodium phosphate buffer, 0.2% gelatin.

Preservative: ≤0.1% sodium azide

Positive Control: HEK293, A-431, HCT116, or HT-1080 cells (full-length APC) or SW480 cells (truncated APC)

Comments: Recognizes all full-length (p300) and truncated (p147) forms of APC.

Ref.: Smith, K.J., et al. 1993. Proc. Natl. Acad. Sci. USA 90, 2846. Su, L.-K., et al. 1993. Can. Res. 53, 2728. Boynton, R.F., et al. 1992. Proc. Natl. Acad. Sci. USA 89, 3385. D'Amico, D., et al. 1992. Cancer Res. 52, 1996. Fearon, E.R., and Jones, P.A. 1992. FASEB J. 6, 2783. Miyoshi, Y., et al. 1992. Proc. Natl. Acad. Sci. USA 89, 4452. Powell, S.M., et al. 1992. Nature 359, 235. Groden, J., et al. 1991. Cell 66, 589. Kinzler, K.W., et al. 1991. Science 253, 661. Nishisho, I., et al. 1991. Science 253, 665.