Anti-CIP1
Anti-p21
Anti-SD11
Anti-WAF

Host: Mouse

Isotype: IgG1

Immunogen: full-length, recombinant, human p21WAF1

Epitope: within amino acids 58-77 of human p21WAF1

Form: Liquid

Formulation: In 50 mM sodium phosphate buffer, 50% glycerol.

Preservative: None

Positive Control: Any cell line expressing wild-type p53 (e.g. Hs27 cells or U2OS cells treated with DNA damaging agents) or UV-treated skin or colon tissue

Negative Control: Unstimulated cells, unstimulated skin tissue, or SK-OV-3 cells

Comments: Recognizes the ~21 kDa p21WAF1 protein in skin and colon tissue and in cells expressing wild-type p53 (e.g. Hs27 or U205 cells treated with DNA damaging agents).

Ref.: Agarwal, M.L., et al. 1995. Proc. Natl. Acad. Sci. USA 92, 8493. Chen, Y.Q., et al. 1995. Int. J. Oncology 7, 889. Deng, C., et al. 1995. Cell 82, 675. Waldman, T., et al. 1995. Cancer Res. 55, 5187. Elbendary, A., et al.1994. Cell Growth Diff. 5, 1301. El-Deiry, W.S., et al. 1994 Cancer Res. 54, 1169. Li, R., et al. 1994. Nature 371, 534. Michieli, P., et al. 1994. Cancer Res. 54, 3391. Noda, A., et al.1994. Exp. Cell Res. 211, 90. El-Deiry, W.S., et al.1993. Cell 75, 817. Gu, Y., et al. 1993. Nature 366, 707. Harper, J.W., et al.1993. Cell 75, 805. Xiong, Y., et al.1993. Genes Devel. 7, 1572. Xiong, Y., et al.1993. Nature 366, 701. Xiong, Y., et al.1992. Cell 71, 505.