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  Anti-Bcl-2 (Ab-3) Mouse mAb (4D7)
Cat. No. OP91  
All Categories » Calbiochem » Antibodies » Primary Antibodies » Apoptotic Pathway Proteins » Bcl-2 & Related Proteins

Host: Mouse
Isotype: IgG1
Immunogen: a synthetic peptide (ASRDPVARTSPLQTPA) corresponding to amino acids 61-76 of human Bcl-2
Form: Liquid
Formulation: In 50 mM sodium phosphate buffer, 0.2% gelatin, pH 7.5.
Preservative: ≤0.1% sodium azide
Positive Control: MCF-7 cells or breast carcinoma or lymph node tissue
Negative Control: Brain tissue
Comments: Recognizes the ~24-26 kDa Bcl-2 protein in MCF-7 cells, breast carcinoma, and lymph node tissue.
Ref.: Larsen, C.J., et al. 1993. Nouv. Rev. Fr. Hematol. 35, 37. Kozopas, K.M., et al. 1993. Proc. Natl. Acad. Sci. USA 90, 3516. Silverman, G.A., et al. 1993 Mol. Cell. Biol. 13, 5469. Wagner, A.J., et al. 1993. Mol. Cell. Biol. 13, 2432. Vaux, D.L., 1993. Proc. Natl. Acad. Sci. USA 90, 786. Hockenberry, D.M., et al. 1991. Proc. Natl. Acad. Sci. USA 88, 6961. Reed, J.C., et al. 1991. Exp. Cell. Res. 195, 277. Reed, J.C., et al. 1990. Mol. Cell. Biol. 10, 4370. Nunez, G., et al. 1989. Proc. Natl. Acad. Sci. USA 86, 4589.

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EMD Chemicals Inc. list price is displayed (pricing with local distributors may vary). NOTE: In Stock status is based on item availability worldwide.

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100 µgYN/A

CloneSpecies ReactivityApplication
4D7 human 
not mouse, not rat 
FC, IB, IF, IP, PS 
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Material Safety Data Sheets:
OP91: Anti-Bcl-2 (Ab-3) Mouse mAb (4D7) - English
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Related Categories:
All Categories » Calbiochem » Antibodies » Primary Antibodies » Apoptotic Pathway Proteins » Bcl-2 & Related Proteins

Selected Citations:
  1. Wayne D. Thomas, et al. (2000) TNF-Related Apoptosis-Inducing Ligand-Induced Apoptosis of Melanoma is Associated with Changes in Mitochondrial Membrane Potential and Perinuclear Clustering of Mitochondria. Journal of Immunology 165, 5612-5620.