Anti-Breast Cancer Susceptibility Protein | Host: Mouse | | Isotype: IgG1 | | Immunogen: recombinant, human BRCA1 | | Epitope: within amino acids 1-304 | | Form: Liquid | | Formulation: In 0.05 M sodium phosphate buffer, 0.2% gelatin. | | Preservative: ≤0.1% sodium azide | | Positive Control: MCF7 cells | | Comments: Recognizes the ~220 kDa BRCA1 protein in MCF-7 cells. Does not react with blood group antigens or growth factor receptors such as EGFR. Sold under license of U.S. Patent 5,753,441 and 6,162,897. | | Ref.: Scully, R., et al. 1996. Science 272, 123. Gudas, J.M., et al. 1996. Cell Growth Differ. 7, 717. Vaughn, J.P., et al. 1996. Cell Growth Differ. 7, 711. Goldgar, D.E. and Reilly, P.R. 1995. Nat. Genet. 11, 113. Merajver, S.D., et al. 1995. Clin. Can. Res. 1, 539. Merajver, S.D., et al. 1995. Nat. Genet. 9, 439. Struewing, J.P., et al. 1995. Nat. Genet. 11, 198. Thompson, M.E., et al. 1995. Nat. Genet. 9, 444. Futreal, P.A., et al. 1994. Science 266, 120. Miki, Y., et al. 1994. Science 266, 66. | | Sold under license of U.S. Patents 5,753,441 and 6,162,897. | |