Anti-Breast Cancer Susceptibility Protein

Host: Mouse

Isotype: IgG2b

Immunogen: a recombinant protein consisting of amino acids 1651-1821 of human BRCA2 fused to GST

Form: Liquid

Formulation: In 0.05 M sodium phosphate buffer, 0.2% gelatin.

Preservative: ≤0.1% sodium azide

Positive Control: MCF7 cells

Comments: Recognzies the ~460 kDa BRCA2 protein in cells expressing a wild type BRCA2 gene. Sold under license of U.S. Patent 5,753,441 and 6,162,897.

Ref.: Andres, J.L., et al. 1998. Oncogene 16, 2229. Chen, J., et al. 1998. Mol. Cell 2, 317. Chen, P.L., et al. 1998. Proc. Natl. Acad. Sci. USA 95, 5287. Marmorstein, L.Y., et al. 1998. Proc. Natl. Acad. Sci. USA 95, 13869. Connor, F., et al. 1997. Nat. Genet. 17, 423. Sharan, S.K., et al. 1997. Nature 386, 804. Ludwig, T., et al. 1997. Genes Dev. 11, 1226. Mizuta, R., et al. 1997. Proc. Natl. Acad. Sci. USA 94, 6927. Rajan, J.V., et al. 1997. Dev. Biol. 184, 385. Suzuki, A., et al. 1997. Genes Dev. 11, 1242. Wong, A.K.C., et al. 1997. J. Biol. Chem. 272, 31941. Cannon-Albright, L.A. and M.H. Skolnick. 1996. Semin. Oncol. 23, 1. Goggins, M., et al. 1996. Cancer Res. 56, 5360. Stratton, M.R. 1996. Hum. Mol. Genet. 5, 1515. Tavtigian, S.V., et al. 1996. Nat. Genet. 12, 333. Rajan, J.V., et al. 1996. Proc. Natl. Acad. Sci. USA 93, 13078. Spillman, M.A. and A.M. Bowcock. 1996. Oncogene 13, 1639. Vaughn, J.P., et al. 1996. Cancer Res. 56, 4590. Wooster, R., et al. 1995. Nature 378, 789.

S: A09

Sold under license of U.S. Patents 5,837,492 and 6,124,104.