Anti-CASP4
Anti-ICErel-II
Anti-ICH-2
Anti-TX Protease

Host: Rabbit

Isotype: IgG

Immunogen: a synthetic peptide (MAEGNHRKKPLKVL) corresponding to amino acids 1-14 of human caspase-4

Form: Liquid

Formulation: Undiluted serum.

Preservative: ≤0.1% sodium azide

Positive Control: Dexamethasone-induced MCF7 cells

Comments: Recognizes the ~52 kDa latent and the ~20 kDa cleaved forms of caspase-4 in doxorubicin-treated MCF-7 cells.

Ref.: Duan, H. and Dixit, V.M. 1997. Nature 385, 86. Fernandes-Alnemri, T., et al. 1997. Cancer Res. 55, 2737. Jung, Y.K. and Yuan, J. 1997. Oncogene 14, 1207. MacFarlane, M., et al. 1997. J. Cell. Biol. 137, 469. Srinivasula, S.M., et al. 1997. Proc. Natl. Acad. Sci. USA 93, 14486. Jung, Y., et al. 1996. J. Biol. Chem. 271, 5112. Tiso, N., et al. 1996. Biochem. Biophys. Res. Commun. 225, 983. Wang, L., et al. 1995. Cell 78, 739.