| Host: Rabbit | | Isotype: IgG | | Immunogen: a synthetic peptide (KLVVVGADGVGK) corresponding to amino acids 5-16 of Ras (H, K, or N) with Asp at position 12 | | Form: Lyophilized | | Formulation: Lyophilized from 20 mM ammonium bicarbonate, 100 µg BSA. | | Preservative: None | | Positive Control: HS78T cells or purified recombinant K-Ras Asp12 protein | | Negative Control: SW480 cells | | Comments: Recognizes the ~21 kDa H-, K-, and N-Ras proteins containing aspartic acid at position 12. | | Ref.: Bos, J.L., et al. 1988. Mutation Res. 195, 255. Furth, M.E., et al. 1987. Oncogene 1, 47. Shimizu, K., et al. 1983. Proc. Natl. Acad. Sci. USA 80, 2112. Taparowsky, E., et al. 1983. Cell 34, 581. Ellis, R.W., et al. 1981. Nature 292, 506. Shih, T.Y., et al. 1990 Nature 287, 686. | |