Anti-ErB3
Anti-Erythroblastosis Virus
Anti-HER3
Anti-Human Epidermal Growth Factor

Host: Rabbit

Isotype: IgG

Immunogen: a synthetic peptide (PPDDKQLLYSEAKT) corresponding to amino acids 860-873 within the kinase domain of human ErbB3

Form: Lyophilized

Formulation: Lyophilized from a volatile buffer, 100 µg BSA.

Preservative: ≤0.1% sodium azide

Positive Control: SK-BR-3 cells

Comments: Recognizes the ~185 kDa ErbB3/HER3 protein in SK-BR-3 cells. Does not recognize c-ErbB2/c-Neu or the EGF receptor.

Ref.: Ciardiello, F., et al. 1991. Proc. Natl. Acad. Sci. USA 88, 7792. Plowman, G.D., et al. 1990. Proc. Natl. Acad. Sci. USA 87, 4905. Kraus, M.H., et al. 1989. Proc. Natl. Acad. Sci. USA 86, 9193. Shoyab, M., et al. 1989. Science 243, 1074. Kawakami, T. and Pennington, C.Y. 1986. Mol. Cell. Biol. 6, 4195.