Host: Rabbit

Isotype: IgG

Immunogen: a synthetic peptide corresponding to amino acids near the C-terminus of human IkBa

Form: Liquid

Formulation: In 0.05 M sodium phosphate buffer, 0.2% gelatin.

Preservative: ≤0.1% sodium azide

Positive Control: HeLa cells treated with ionomycin + PMA

Comments: Recognizes the ~36-38 kDa IkBa protein in ionomycin and PMA-treated HeLa cells.

Ref.: Baldwin, A. 1996. Ann. Rev. Immunol. 14, 649. Arenzana-Seisdedos, F., et al. 1995. Mol. Cell Biol. 15, 2689. Matthews, J.R. and Hay, R.T. 1995. Int. J. Biochem. Cell Biol. 27, 865. Steffan, N.M., et al. 1995. J. Immunol. 15, 4685. Chaio, P.J., et al. 1994. Proc. Natl. Acad. Sci. USA 91, 28.