| Host: Rabbit | | Isotype: IgG | | Immunogen: a synthetic phosphopeptide corresponding to amino acids surrounding the Ser15 phosphorylation site of human p53, conjugated to KLH | | Form: Liquid | | Formulation: In 150 mM NaCl, 10 mM sodium HEPES, 100 µg/ml BSA, 50% glycerol, pH 7.5. | | Preservative: None | | Positive Control: PC-12, HCT116, or HeLa cells treated with DNA damaging agents | | Comments: Recognizes the ~53 kDa p53 protein phosphorylated at Ser15 in PC12 or HeLa cells treated with DNA damaging agents. Does not recognize unphosphorylated p53. | | Ref.: Tibbetts, R.S., et al. 1999. Genes Dev. 13, 152. Levine, A.J. 1997. Cell 88, 323. Milczarek, G.J., et al. 1997. Life Sci. 60, 1. Shieh, S.Y., et al. 1997. Cell 91, 325. Meek, D.W. 1994. Semin Cancer Biol. 5, 203. |
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