| Host: Rabbit | | Isotype: IgG | | Immunogen: a synthetic phosphopeptide [KKKSPGEpYVNIEFG(C)] corresponding to amino acids 891-902 surrounding the Tyr896 phosphorylation site of human insulin receptor substrate-1 (hIRS-1) | | Form: Liquid | | Formulation: Serum diluted in PBS. | | Preservative: None | | Positive Control: MCF7 cells | | Comments: Recognizes IRS phosphorylated at Tyr896 in MCF-7 cells | | Ref.: Goldstein, B. J., et al. 2000. J. Biol. Chem. 275, 4283. Ueno, H., et al. 2000. Mol. Biol. Cell 11, 735. Paz, K., et al. 1999. J. Biol. Chem. 274, 28816. Lavan, B. E., et al. 1997. J. Biol. Chem. 272, 11439. Lavan, B. E., et al. 1997. J. Biol. Chem. 272, 21403. White, M. F., 1997. Diabetologia 40, S2. Cheatham, B., and Kahn, C. R., 1995. Endocr. Rev. 16, 117. Sun, X. J., et al. 1995. Nature 377, 173. Sun, X. J., et al. 1991. Nature 352, 73. | |