| Host: Rabbit | | Isotype: IgG | | Immunogen: a synthetic peptide (GWIQDQGGWDGLLSYF) corresponding to amino acids 150-165 of human Bax | | Form: Liquid | | Formulation: In 0.05 M sodium phosphate buffer, 0.2% gelatin. | | Preservative: ≤0.1% sodium azide | | Positive Control: Doxorubicin-treated HeLa or MCF7 cells, mouse intestinal tissue, or human lymph node tissue | | Negative Control: Uninduced HeLa or MCF-7 cells | | Comments: Recognizes the ~21 kDa monomeric and ~44 -50 kDa dimeric Bax protein in induced HeLa and MCF-7 cell lysates. | | Ref.: Bargou, R.C., et al. 1995. Int. J. Cancer 60, 854. Hanada, M., et al. 1995. J. Biol. Chem. 270, 11962. Miyashita, T. and Reed, J.C. 1995. Cell 80, 293. Korsmeyer, S.J., et al. 1993. Semin. Cancer Biol. 4, 327. Oltvai, Z.N., et al. 1993. Cell 74, 609. | |