Anti-Protein Tyrosine Phosphatase 1B

Host: Mouse

Isotype: IgG2a

Immunogen: recombinant, human protein tyrosine phosphatase 1B

Epitope: within the catalytic domain

Form: Liquid

Formulation: In 0.05 M sodium phosphate buffer, 0.2% gelatin.

Preservative: ≤0.1% sodium azide

Positive Control: BSC-40 cells

Comments: Recognizes the ~50 kDa PTPase 1B protein. Weak reactivity with mouse PTPase 1B and human TC/PTPase (a 48 kDa protein).

Ref.: Flint, A.J., et al. 1993. EMBO J. 12, 1937. Brown-Shimer, S., et al. 1992. Cancer Res. 52, 478. Fischer, E.H., et al. 1991. Science 253, 401. Pallen, C.J., et al. 1991. Biochem. J. 276, 315. Brown-Shimer, S., et al. 1990. Proc. Natl. Acad. Sci. USA 87, 5148. Chernoff, J., et al. 1990. Proc. Natl. Acad. Sci. USA 87, 2735. Charbonneau, H., et al. 1989. Proc. Natl. Acad. Sci. USA 86, 5252. Charbonneau, H., et al. 1988. Proc. Natl. Acad. Sci. USA 85, 7182.