Anti-Abl1, Phospho-Specific (Tyr245)
Anti-c-Abl, Phospho-Specific (Tyr245)
Anti-p150, Phospho-Specific (Tyr245) | Host: Rabbit | | Isotype: IgG | | Immunogen: a synthetic phosphopeptide corresponding to amino acids surrounding the Tyr245 phosphorylation site of human c-Abl, coupled to KLH | | Form: Liquid | | Formulation: In 150 mM NaCl, 10 mM sodium HEPES, 100 µg/ml BSA, 50% glycerol, pH 7.5. | | Preservative: None | | Positive Control: HEK293 cells over-expressing constitutively active c-Abl and K562 cells (BCR-Abl) | | Comments: Recognizes the ~135 kDa c-Abl protein phosphorylated at Tyr245 in HEK293 cells over-expressing constitutively active c-Abl. Also recognizes the ~210 kDa BCR-Abl protein phosphorylated at Tyr245 in K562 cells. | | Ref.: Pluk, H., et al. 2002. Cell 108, 247. Brasher, B.B. and Van Etten, R.A. 2000. J. Biol. Chem. 275, 35631. Danial, N.N. and Rothman, P. 2000. Oncogene 19, 2523. Shaul, Y. 2000. Cell Death Differ. 7, 10. Wang, J.Y. 2000. Oncogene 19, 5643. Van Etten, R.A. 1999. Trends Cell. Biol. 9, 179. |
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