Anti-Janus Kinase 2, Phospho-Specific (Tyr1007/1008 | Host: Rabbit | | Isotype: IgG | | Immunogen: a synthetic phosphopeptide corresponding to amino acids surrounding the Tyr1007/1008 phosphorylation sites of human JAK2 | | Form: Liquid | | Formulation: In Dulbecco's PBS (without Mg2+ and Ca2+), 50 % glycerol, 1 mg/ml BSA, pH 7.3 (± 0.1). | | Preservative: ≤0.1% sodium azide | | Positive Control: 3T3-L1 adipocytes stimulated with leukemia inhibitor factor (LIF) | | Comments: Recognizes the ~130 kDa JAK2 protein phosphorylated at Tyr1007/1008 in LIF-treated 3T3-L1 cells. | | Ref.: Frank, G.D., et al. 2003. Mol. Biol. 23, 1581. Kaszubska, W., et al. 2002. Mol. Cell. Endocrinol. 195, 109. Kirito, K., et al. 2002. J. Biol. Chem. 277, 8329. Shaw, S., et al. 2002. J. Biol. Chem. 277, 44920. Sutherland, C.L., et al. 2002. J. Immunol. 168, 671. Zeng, Z.Z., et al. 2002. J. Biol. Chem. 277, 41213. Eguchi, S., et al. 2001. J. Biol. Chem. 276, 7957. Madamanchi, N.R., et al. 2001. J. Biol. Chem. 276, 18915. Myers, M.P., et al. 2001. J. Biol. Chem. 276, 47771. Madamanchi, N.R., et al. 2000. Arterioscler. Thromb. Vasc. Biol. 21, 321. Amiri, F., et al. 1999. J. Biol. Chem. 274, 32382. Ihle, J.N., et al. 1996. Cell 84, 331. | |