uPA Activity Assay Kit, Fluorogenic
Urokinase-Type Plasminogen Activator Activity Assay Kit, Fluorogenic

Format: 96-well plate

Form: 100 Tests

Detection Method: Fluorometric

Species Reactivity: human

Sensitivity: 0.01 U/ml

Assay Range: 0.78 - 50 U/ml

Assay Time: 1.5 h

Sample Type: Cell lysates, plasma, and serum, for screening uPA inhibitors

Positive Control: Urokinase

Kit Contents: Urokinase Standard, Substrate, Assay Buffer, Dilution Buffer, Microplate, Plate Sealer, Cell Lysis Buffer, and a user protocol.

Comments: A sensitive fluorogenic assay for the measurement of urokinase activity (Excitation: ~360-380 nm; Emission: ~430-460 nm). Altered activity of urokinase has been implicated in several physiological and pathological processes including inflammation, angiogenesis, tissue remodeling, and tumor metastasis.

Ref.: Meuhlenweg, B., et al. 2001. Expert Opin. Biol. Ther. 1, 683. Dano, K., et al. 1994. Fibrinolysis 8 (supp. 1), 189. Dano, K., et al. 1985. Adv. Cancer Res. 44, 139 Morita, T., et al. 1977. J. Biochem. 82, 1495. Johnson, A.J., et al. 1969. Thromb. Diath. Haemorrh. 21, 259.

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