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| | PhosphoDetect™ Anti-PTEN (pSer380) Rabbit pAb |
|  | Cat. No. ST1072 |
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Anti-MMAC, Phospho-Specific (Ser380)
Anti-Phosphatase and Tensin Homologue Deleted on Chromosome Ten, Phospho-Specific (Ser380) | Host: Rabbit | | Isotype: IgG | | Immunogen: a synthetic phosphopeptide corresponding to amino acids surrounding the Ser380 phosphorylation site of human PTEN | | Form: Liquid | | Formulation: In 150 mM NaCl, 10 mM HEPES, 100 µg/ml BSA, 50% glycerol, pH 7.5. | | Preservative: None | | Positive Control: HeLa, PC12, or NIH 3T3 cells | | Comments: Recognizes the ~54 kDa PTEN protein phosphorylated at Ser380. | | Ref.: Sansal, I. and Sellers, W.R. 2004. J. Clin. Oncol. 22, 2954. Birle, D., et al. 2002. J. Immunol. 169, 286. Torres, J. and Pulido, R. 2001. J. Biol. Chem. 276, 993. Vasquez, F., et al. 2000. Mol. Cell. Biol. 20, 5010. Cantley, L.C. and Neel, B.G. 1999. Proc. Natl. Acad. Sci. USA 96, 4240. |
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EMD Chemicals Inc. GBP list price is displayed (pricing with local distributors may vary). NOTE: In Stock status is based on item availability worldwide.
| | human, mouse, rat | IB, IC, IP, PS
See Key |
Detection of human PTEN, phosphorylated at Ser380, by immunoblotting. Samples: Whole cell lysate from C6, HeLa, 293, SW-13, PC12, (all untreated) and NIH 3T3 cells untreated or treated with calf intestine alkaline phosphatase (CIP). Primary antibody: PhosphoDetect™ Anti-PTEN (pSer380) Rabbit pAb (Cat. No. ST1072) (1:1000). Detection: chemiluminescence.
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