Anti-Protein Tyrosine Phosphatase 2C, Phospho-Specific (Tyr⁵⁴²)

Host: Rabbit

Isotype: IgG

Immunogen: a synthetic peptide corresponding to amino acids surrounding the Tyr542 phosphorylation site of human SHP-2

Form: Liquid

Formulation: In 150 mM NaCl, 10 mM HEPES, 100 µg/ml BSA, 50% glycerol, pH 7.5.

Preservative: None

Positive Control: C6 or NIH3T3 cells serum-starved treated with PDGF

Comments: Recognizes the ~72 kDa SHP-2 protein phosphorylated at Tyr542 in serum-starved PDGF-treated C6 and NIH3T3 cells.

Ref.: Lu, W., et al. 2003. Biochemistry 42, 5461. MacGillivray, M., et al. 2003. J. Biol. Chem. 278, 27190. Lu, W., et al. 2001. Mol. Cell 8, 759.